Imidazodiazepines

Details Imidazodiazepines Imidazodiazepines

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/55 (2006.01) C07D 487/14 (2006.01) C07D 495/14 (2006.01) C07D 495/22 (2006.01)

Patent

CA 2143246

Imidazodiazepines of the general formula (see formula I) wherein A and the two carbon atoms denoted by .alpha. and .beta. together signify one of the residues (see formula II) Q signifies one of the residues (see formula III) R1 and R2 each signify hydrogen, lower alkyl, lower alkenyl, lower alkynyl, lower hydroxyalkyl, lower alkoxy-lower alkyl, (C3-C6)-cycloalkyl, (C3-C6)-cycloalkyl-lower alkyl, amino-lower alkyl, lower alkylamino-lower alkyl, di-lower alkylamino-lower alkyl or aryl-lower alkyl or together with the nitrogen atom signify a 5- to 8-membered heterocycle optionally containing a further hetero atom or a fused benzene ring, R3 signifies hydrogen and R4 signifies lower alkyl or R3 and R4 together signify a di- or trimethylene group and R5 and R6 each signify hydrogen, halogen, trifluoromethyl, lower alkoxy or nitro, and the carbon atom denoted by .gamma. has the S-configuration when R3 is different from hydrogen, have pronounced anxiolytic, anticonvulsant, muscle relaxant and sedative-hypnotic properties. They form acid addition salts which have very good water solubility and are therefore particularly suitable for the production of aqueous injection solutions.

Affiliated with

Also associated with

Rating

Imidazodiazepines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Imidazodiazepines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Imidazodiazepines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1701067