Imidazol-4-ylpiperidine derivatives, their preparation and...

Details Imidazol-4-ylpiperidine derivatives, their preparation and... Imidazol-4-ylpiperidine derivatives, their preparation and...

C - Chemistry, Metallurgy

07

D

C07D 498/06 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/55 (2006.01) C07D 471/06 (2006.01) C07D 487/06 (2006.01)

Patent

CA 2133491

38 ABSTRACT IMIDAZOL-4-YLPIPERIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS A compound of formula (I): Image (I) in which R1 represents a hydrogen atom or a straight or branched (C1-C4)alkyl group; and A represents a 5,6-dihydro-4H-imidazo[4,5,1-ij]quinol- 2-yl group, a 4,5-dihydroimidazo[1,5,4- de][1,4]benzoxazin-2-yl group, a 4-methyl-4,5- dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl group, a 4-phenyl-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2- yl group, a 4-phenylmethyl 4,5-dihydroimidazo[1,5,4- de][1,4]benzoxazin-2-yl group, a 5-methyl-4,5- dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl group, a 5,6-dihydro-4H imidazo-[1,5,9 de]quinoxalin-2-yl group, a 6-oxo-5,6-dihydro-4H-imidazo[4,5,1-ij]quinol-2-yl group, or a 5-methyl-4,5,6,7-tetrahydroimidazo[4,5,1- jk][1,4]benzodiazepin-2-yl group which may be unsubstituted or substituted in the 6-position by a phenylmethyl group; or an addition salt thereof with a pharmaceutically acceptable acid.

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