Imidazol derivatives

Details Imidazol derivatives Imidazol derivatives

C - Chemistry, Metallurgy

07

D

C07D 233/90 (2006.01) A61K 31/4164 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2561585

The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10,R11, X and X' which have the meaning cited in claim 1, are tyrosine kinase inhibitors, in particular TIE-2, and Raf-kinases, and can also be used in the treatment of tumours.

L'invention concerne des composés de la formule (I) où R1, R2, R3, R4, R5, R6, R7,R8 R9, R10,R11, X et X' ont la définition donnée dans la revendication 1. Ces composés sont des inhibiteurs de la tyrosine-kinase, notamment TIE-2, et de la Raf-kinase et permettent notamment de traiter des tumeurs.

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