Imidazol derivatives, process for their preparation and...

Details Imidazol derivatives, process for their preparation and... Imidazol derivatives, process for their preparation and...

C - Chemistry, Metallurgy

07

D

C07D 233/64 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/535 (2006.01) C07D 233/54 (2006.01) C07D 233/90 (2006.01) C07D 401/00 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 405/00 (2006.01) C07D 405/04 (2006.01) C07D 405/06 (2006.01) C07D 413/14 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2092309

2092309 9205148 PCTABS00011 Imidazole derivatives of the formula (I): [DPIM]-X-Z-Y wherein [DPIM] is a 4,5-diphenylimidazol-2-yl grouping in which the phenyl groups are optionally substituted by halogen, alkyl or alkoxy, X represents a direct bond or alkylene, alkenylene or alkynylene of up to 3 carbon atoms, Z represents a direct bond or, when X is other than a direct bond, Z represents oxygen, -O-CH2- or -NH-, and Y represents alkoxycarbonyl, optionally substituted alkyl, optionally substituted phenyl or heterocyclyl, or a group of formula (II), (III), (IV), wherein m is 2, 3 or 4, p is 0, 1, 2, 3, 4 or 5, q is 0 or 1, r is 1, 2, 3 or 4, provided that formulae (III) and (IV) each represents a 5-, 6- or 7-membered ring, and Q represents optionally substituted methylene, and pharmaceutically acceptable salts thereof possess useful pharmacological properties.

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