Imidazole-5-carboxylic acid derivatives,the preparation...

Details Imidazole-5-carboxylic acid derivatives,the preparation... Imidazole-5-carboxylic acid derivatives,the preparation...

C - Chemistry, Metallurgy

07

D

C07D 403/10 (2006.01) A61K 31/41 (2006.01) A61K 31/4164 (2006.01) A61P 9/12 (2006.01) C07D 233/68 (2006.01) C07D 233/90 (2006.01) C07D 405/10 (2006.01)

Patent

CA 2643005

The present application discloses a kind of imidazol-5-carboxylic acid derivatives, and preparation methods thereof. The said derivatives are angiotensin II antagonists, which show strongly antagonist activity against angiotensin II, and high antihypertensive activity. So they can be used as therapeutical agents against hypertension.

L'invention concerne un type de dérivés d'acide imidazol-5-carboxylique et leurs procédés de préparation. Ces dérivés sont des antagonistes de l'angiotensine II qui présentent une importante activité antagoniste contre l'angiotensine II et une activité antihypertensive élevée. Ces dérivés peuvent, par conséquent, être utilisé comme agents thérapeutiques contre l'hypertension.

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