Imidazole based lxr modulators

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 233/54 (2006.01) A61K 31/4164 (2006.01) A61P 3/10 (2006.01) C07D 401/04 (2006.01) C07D 409/04 (2006.01)

Patent

CA 2613522

Compounds of the invention, such as compounds of Formulae IIa, IIb, IIc or IId, and pharmaceutically acceptable salts, isomers, and prodrugs thereof, are useful as modulators of the activity of liver X receptors, where R1, R2, R21, R3 and G are defined herein. Pharmaceutical compositions containing the compounds and methods of using the compounds are also disclosed.

La présente invention concerne des composés, tels que ceux de Formule IIa, IIb, IIc ou IId, ainsi que des sels, isomères et prodrogues de qualité pharmaceutique desdits composés, pouvant être employés en tant qu'agents régulateurs de l'activité des récepteurs X du foie, R1, R2, R21, R3 et G étant tel que définis dans la présente invention. La présente invention concerne également des préparations pharmaceutiques contenant lesdits composés et des méthodes d'emploi desdits composés.

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