Imidazole compounds as phosphodiesterase vii inhibitors

Details Imidazole compounds as phosphodiesterase vii inhibitors Imidazole compounds as phosphodiesterase vii inhibitors

C - Chemistry, Metallurgy

07

D

C07D 498/06 (2006.01) A61K 31/5365 (2006.01) A61K 31/542 (2006.01) A61P 37/00 (2006.01) C07D 221/00 (2006.01) C07D 265/00 (2006.01) C07D 279/00 (2006.01) C07D 513/06 (2006.01)

Patent

CA 2391087

The invention relates to the use of imidazole compounds of formula (I), wherein: R1 and R2, independent of one another, represent H, A1, OA1, SA1 or Hal; A1 represents H, A, alkenyl, cycloalkyl or alkylene cycloalkyl; A represents alkyl having 1-10 C atoms; Hal represents F, Cl, Br or I, and; X represents O, S, SO or SO2, as well as the physiologically compatible salts and/or solvates of said imidazole compounds as phosphodiesterase VII inhibitors, and to their use for producing a medicament.

L'invention concerne des composés imidazole de formule (I), ainsi que leurs sels ou solvates physiologiquement compatibles, utilisés comme inhibiteurs de la phosphodiestérase VII et leur utilisation pour la production d'un médicament. Dans la formule (I), R?1¿ et R?2¿ représentent indépendamment l'un de l'autre H, A?1¿, OA?1¿, SA?1¿ ou Hal, A?1¿ représente H, A, alcényle, cycloalkyle ou alkylène cycloalkyle, A représente alkyle ayant 1 à 10 atomes de carbone, Hal représente F, Cl, Br ou I et X représente O, S, SO ou SO¿2?.

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