Imidazole compounds, their preparation and use

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 235/30 (2006.01) A61K 31/415 (2006.01)

Patent

CA 2084233

Abstract The present invention discloses compounds of the formula Image wherein R' and R" independently of each other are hydrogen or alkyl, or R' and R" together form a 3 to 6 membered alkylene chain; n is 1 or 2; R1 is phenyl which may be substituted one or more times with halogen, CF3, alkoxy, alkyl, or amino; and R4, R5, R6 and R7 independently of each other are hydrogen, halogen, amino, CF3,alkyl or alkoxy; or a pharmaceutically-acceptable addition salt thereof. The compounds are useful as pharmaceuticals, for example, in the treatment of ischemia, anoxia, migraine and psychosis.

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