C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/302, 260/305
C07D 235/02 (2006.01) C07D 213/26 (2006.01) C07D 213/30 (2006.01) C07D 403/12 (2006.01)
Patent
CA 1106849
ABSTRACT Compounds of the formula I Image wherein R1, R2, R3 and R4 each denotes hydrogen or R1 together with R2and R3 together with R4 each denotes an additional carbon-carbon bond, n is the number 0 or 1, R5 denotes hydrogen or lower alkyl, and X denotes a 2-pyridyl radical optionally mono- substituted by lower alkyl, a 2-imidazolyl radical, a 2-imidazolinyl radical, a 2-thiazolyl radical, a 2-thiazolinyl radical, or a 4(5)-imidazolyl radical optionally mono- substituted by lower alkyl, as well as their acid addition salts inhibit gastric secretion and can be used to treat gastric ulcers.
311181
Krasso Anna
Krebs Ernst-Peter
Gowling Lafleur Henderson Llp
Hoffmann-La Roche Limited
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