C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/314.7
C07D 233/84 (2006.01) C07D 233/54 (2006.01) C07D 263/42 (2006.01)
Patent
CA 1096388
ABSTRACT OF THE DISCLOSURE Novel 4,5-disubstituted imidazole-2-thiones of the formula Image wherein R is methyl or ethyl; n is 2, 3, 4, or 5; and Q is hydrogen or a benzoyl group, are provided herein. These compounds are useful inter- mediates for the production of compounds having pharmacological activity at histamine R2 receptors, the activity being either as agonists or as antagonists.
293537
King Ronald J.
White George R.
Marcus & Associates
Smith Kline & French Laboratories Limited
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