Imidazole derivatives and a process for their production

C - Chemistry – Metallurgy – 07 – D

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260/298.3

C07D 491/048 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01) C07F 7/10 (2006.01)

Patent

CA 1322756

IMIDAZOLE DERIVATIVES AND A PROCESS FOR THEIR PRODUCTION ABSTRACT Imidazole derivatives and a process for their production. The derivatives have the formula: Image IX wherein R1 is an (R)- or (S)-1-phenylalkyl group, an (R)- or (S)-1-alkoxycarbonyl-1-phenylmethyl group or an (R)- or (S)-1-aryloxycarbonyl-1-phenylmethyl group, R2 is hydrogen, a substituted or unsubstituted alkanoyl group, and unsubstituted or a substituted benzoyl group, a substituted or an unsubsti- tuted benzyl group, an alkoxycarbonyl group, and aryloxy- carbonyl group, an alkoxyalkyl group, a pyranyl group, a substituted or unsubstituted benzenesulfonyl group, an alkylsulfonyl group, a diarylphosphinyl group, a dialkoxy- phosphinyl group or a trialkylsilyl group, and A is a sulfur or oxygen atom. The derivatives are suitable particularly as intermediate products for the production of (+) biotin.

553241

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