Imidazole derivatives as enzyme reverse transcriptase...

Details Imidazole derivatives as enzyme reverse transcriptase... Imidazole derivatives as enzyme reverse transcriptase...

C - Chemistry, Metallurgy

07

D

C07D 233/84 (2006.01) A61K 31/4164 (2006.01)

Patent

CA 2592909

This invention relates to benzonitrile derivatives of formula (I) or pharmaceutically acceptable salts, solvates or derivative thereof, wherein R1 to R3 are defined in the description, to their use in medicine, and to compositions containing them. The compounds of the present invention bind to the enzyme reverse transcriptase and are modulators, especially inhibitors thereof.

L'invention concerne des dérivés de benzonitrile de formule (I) ou des sels acceptables pharmaceutiquement, des solvates ou des dérivés associés. Dans ladite formule, R1 à R3 sont tels que définis dans la description. Cette invention a aussi trait à l'utilisation desdits dérivés en médecine et aux compositions les renfermant. Ces composés peuvent se lier à la transcriptase inversée d'enzyme et constituent des modulateurs, notamment, des inhibiteurs correspondants.

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