Imidazole derivatives as mdr modulators

Details Imidazole derivatives as mdr modulators Imidazole derivatives as mdr modulators

C - Chemistry, Metallurgy

07

D

C07D 233/64 (2006.01) A61K 31/395 (2006.01) A61K 31/415 (2006.01) A61K 31/4164 (2006.01) A61P 35/00 (2006.01) C07D 235/18 (2006.01) C07D 413/10 (2006.01) C07D 413/14 (2006.01) C07D 417/10 (2006.01)

Patent

CA 2295625

The present invention relates to imidazole derivatives having formula (1) or its pharmaceutically acceptable salts. These compounds are useful for restoring the sensitivity of multidrug resistant cells to cancer chemotherapeutic agents.

La présente invention concerne des dérivés d'imidazole répondant à la formule (1) ou leurs sels pharmaceutiquement acceptables. Ces composés sont utilisés pour restaurer la sensibilité aux agents de chimiothérapie anti-cancéreuse des cellules présentant une résistance multiple aux anti-cancéreux.

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