A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4164 (2006.01) A61P 11/06 (2006.01) A61P 35/00 (2006.01) A61P 37/08 (2006.01) C07D 233/00 (2006.01)
Patent
CA 2521841
The preferred embodiments are directed to small molecule inhibitors of the IgE response to allergens, which are useful in the treatment of allergy and/or asthma or any diseases where IgE is pathogenic. The preferred embodiments also relate to imidazole molecules that are cellular proliferation inhibitors and thus are useful as anticancer agents. The preferred embodiments further relate to small molecules which suppress cytokines and leukocytes.
Dans ses modes de réalisation préférés, cette invention concerne des inhibiteurs de petites molécules de la réaction IgE à des allergènes, utiles dans le traitement d'allergies et/ou d'asthmes ou n'importe quelle maladie dans laquelle l'IgE est pathogène. Ces modes de réalisation préférés concernent également des molécules imidazole qui sont des inhibiteurs de prolifération cellulaire et donc utiles en tant qu'agents anticancéreux. Ces modes de réalisation concernent enfin des petites molécules qui suppriment les cytokines et les leucocytes.
Khatuya Haripada
Richards Mark L.
Sircar Jagadish C.
Thomas Richard J.
Avanir Pharmaceuticals
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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