Imidazole derivatives having affinity for alpha 2 receptors...

C - Chemistry – Metallurgy – 07 – D

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C07D 233/64 (2006.01) A61K 31/4164 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) C07D 233/54 (2006.01) C07D 233/56 (2006.01)

Patent

CA 2508335

The present invention relates to novel prodrugs of MPV-2426, to methods for preparing said prodrug forms, to pharmaceutical compositions containing such forms, and to methods for using the prodrug forms. A compound of general formula (I), or pharmaceutically acceptable salts hydrates thereof, wherein R represents unsubstituted or substituted lower alkyl, unsubstituted or substituted aryl, unsubstituted or substituted cycloalkyl, unsubstituted or substituted heteroaryl, unsubstituted or substituted lower alkylamino or a saturated five or six membered heterocyclic group containing one or two nitrogen atoms.(see formula I)

La présente invention concerne de nouveaux promédicaments de MPV-2426, des procédés pour produire ces formes de promédicaments, des compositions pharmaceutiques contenant de telles formes de promédicaments et des procédés pour utiliser lesdites formes de promédicaments.

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