Imidazole-derivatives having agonistic or antagonistic...

Details Imidazole-derivatives having agonistic or antagonistic... Imidazole-derivatives having agonistic or antagonistic...

C - Chemistry, Metallurgy

07

D

C07D 233/54 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) C07D 233/68 (2006.01) C07D 233/90 (2006.01) C07D 233/94 (2006.01) C07D 233/95 (2006.01) C07D 401/02 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2104946

2104946 9215567 PCTABS00016 The invention relates to imidazole-derivatives of general formula (a). The invention in particular relates to derivatives having agonistic or antagonistic activity on the histamine H3-receptor. The novel imidazole-derivatives are isothio urea-, guanidine- and amidine-derivatives. The invention further relates to pharmaceutical compositions comprising the novel imidazole-derivatives as well as to methods for preparing the derivatives and for preparing pharmaceutical compositions having antagonistic and agonistic activity on the histamine H3-receptor.

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