Imidazole derivatives having anti-hiv activity

Details Imidazole derivatives having anti-hiv activity Imidazole derivatives having anti-hiv activity

C - Chemistry, Metallurgy

07

D

C07D 233/54 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) C07D 233/80 (2006.01) C07D 233/84 (2006.01) C07D 233/86 (2006.01) C07D 233/90 (2006.01) C07D 401/02 (2006.01) C07D 401/06 (2006.01) C07D 403/02 (2006.01) C07D 403/06 (2006.01) C07D 413/02 (2006.01) C07D 413/06 (2006.01) C07D 417/02 (2006.01) C07D 417/06 (2006.01)

Patent

CA 2087112

- 89 - Abstract of Disclosure A novel imidazole derivatives of formula I: Image I wherein R1 is hydrogen, alkyl, halogen, or optionally substituted aryl; R2 is alkyl, optionally substituted aryl optionally substituted aralkyl, or optionally substituted hetero ring group; R3 is hydrogen, alkyl, optionally substituted aryl, optionally substituted aralkyl, or optionally substituted hydroxyalkyl; R4 is hydrogen, alkyl, halogen, acyl, optionally substituted hydroxyalkyl, optionally esterified or amidated carboxyl group, hydroxy group, aryl or arylthio; X is S, SO, SO2, CH2, or Se; n is an integer of 1 to 3, or a pharmaceutically acceptable salt thereof, said derivative having anti-HIV activity and being useful for the treatment of HIV infections.

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