Imidazole derivatives or their salts

Details Imidazole derivatives or their salts Imidazole derivatives or their salts

C - Chemistry, Metallurgy

07

D

C07D 233/60 (2006.01) A61K 31/4164 (2006.01) A61P 37/04 (2006.01) A61P 43/00 (2006.01) C07D 233/54 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2420945

Imidazole derivatives of the general formula (1) or salts thereof, medicines containing the derivatives or the salts, and intermediates for the synthesis of the derivatives or the salts (wherein R1 is lower alkyl; R2 is alkyl or aralkyl; and X1 is halogeno). These compounds exhibit G-CSF-like activities and can be substituted for G-CSF preparations.

L'invention concerne des dérivés imidazoles correspondant à la formule générale (1), ou des sels de ceux-ci, des médicaments contenant ces dérivés ou sels, ainsi que des intermédiaires destinés à la synthèse de ces dérivés ou sels. Dans cette formule, R?1¿ représente alkyle inférieur, R?2¿ représente alkyle ou aralkyle, et X?1¿ représente halogéno. Ces composés démontrent des activités de type G-CSF et on peut les substituer à des préparations G-CSF.

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