C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/435 (2006.01)
Patent
CA 2570619
Box No. IV Text of the abstract (Continuation of item 5 of the first sheet) The present invention relates to novel compounds having a positive allosteric GÀBAB receptor (GDR) modulator effect, methods for the preparation of said compounds and to their use, optionally in combination with a GABAB agonist, for the inhibition of transient lower esophageal sphincter relaxations, for the treatment of gastroesophageal reflux disease, as well as for the treatment of functional gastrointestinal disorders and irritable bowel syndrome (IBS). A compound of the general formula I
La présente invention concerne de nouveaux composés présentant un effet modulateur du récepteur GABA<SB>B</SB> (GBR) allostérique positif, des procédés de préparation de ces composés ainsi que leur utilisation, éventuellement en combinaison avec un agoniste GABA<SB>B</SB>, pour l'inhibition des relâchements transitoires du sphincter oesophagien inférieur, pour le traitement du reflux gastro-oesophagien et pour le traitement de troubles gastro-intestinaux fonctionnels et du syndrome du côlon irritable (SCI). L'invention concerne un composé de formule générale (I).
Bauer Udo
Brailsford Wayne
Chhajlani Vijay
Egner Bryan
Fjellstroem Ola
Astrazeneca Ab
Fetherstonhaugh & Co.
LandOfFree
Imidazole variants as modulators of gaba receptor for the... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Imidazole variants as modulators of gaba receptor for the..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Imidazole variants as modulators of gaba receptor for the... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1744698