C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/72 (2006.01) A61K 31/4166 (2006.01) A61P 35/00 (2006.01) C07D 233/76 (2006.01)
Patent
CA 2758630
The present application relates to novel imidazolidine-2,4-dione derivatives of the general formula (I), where R1, R2, R3, R4, X, and Y are variables. Said materials have an antiproliferative activity. They are particularly useful for treating pathological conditions and diseases, such as cancer, that are linked to abnormal cell proliferation. The invention also relates to pharmaceutical compositions containing said materials and to the use thereof for preparing a drug.
La présente demande a pour objet de nouveaux dérivés d'imidazolidine-2,4-dione de formule générale (I) dans laquelle R1, R2, R3, R4, X, et Y sont des variables. Ces produits ont une activité anti-proliférative. Ils sont particulièrement intéressants pour traiter les états pathologiques et les maladies liés à une prolifération cellulaire anormale tels que les cancers. L'invention concerne également des compositions pharmaceutiques contenant lesdits produits et leur utilisation pour la préparation d'un médicament.
Auvin Serge
Lanco Christophe
Lavergne Olivier
Liberatore Anne-Marie
Prevost Gregoire
Goudreau Gage Dubuc
Ipsen Pharma S.a.s.
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