C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/00 (2006.01)
Patent
CA 2629317
The present invention is directed to imidazolidinone compounds which are inhibitors of the beta- secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
La présente invention concerne des composés d~imidazolidinone qui sont des inhibiteurs de l~enzyme de la béta-secrétase et qui se révèlent très utiles dans le traitement de maladies dans lesquelles l~enzyme de la béta-secrétase est impliquée, telle la maladie d~Alzheimer. L~invention porte également sur des compositions pharmaceutiques renfermant ces composés et sur l~utilisation de ces composés et compositions dans le traitement de maladies dans lesquelles l~enzyme de la béta-secrétase est impliquée.
Barrow James C.
Bondiskey Phung Le
Rittle Kenneth E.
Merck & Co. Inc.
Norton Rose Canada S.e.n.c.r.l.,s.r.l./llp
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