Imidazoline derivative

C - Chemistry – Metallurgy – 07 – D

Patent

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260/305.1

C07D 405/04 (2006.01) C07D 233/04 (2006.01) C07D 319/20 (2006.01)

Patent

CA 1156241

ABSTRACT OF THE DISCLOSURE 2-[2-(1,4-Benzodiaoxyanyl)]-2-imidazoline of the formula Image or a non-toxic salt thereof, substantially free of 2-[2-(2-methyl- 1,3-benzodioxolyl)]-2-imidazoline or a non-toxic salt thereof, the 2-[2-(1,4-benzodioxanyl)]-2-imidazoline or a non-toxic salt thereof characterised in that the nuclear magnetic resonance spectrum of the compound in a protonated form exhibits multiplets in the region of ?4.4 and ?5.4, process for the preparation of 2-[2-(1,4-benzodioxanyl)]-2-imidazoline, pharmaceutical compositions thereof or of its salts, and their use as presynaptic .alpha.2-adrenoreceptor antagonists.

369899

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