C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/305.1
C07D 405/04 (2006.01) C07D 233/04 (2006.01) C07D 319/20 (2006.01)
Patent
CA 1156241
ABSTRACT OF THE DISCLOSURE 2-[2-(1,4-Benzodiaoxyanyl)]-2-imidazoline of the formula Image or a non-toxic salt thereof, substantially free of 2-[2-(2-methyl- 1,3-benzodioxolyl)]-2-imidazoline or a non-toxic salt thereof, the 2-[2-(1,4-benzodioxanyl)]-2-imidazoline or a non-toxic salt thereof characterised in that the nuclear magnetic resonance spectrum of the compound in a protonated form exhibits multiplets in the region of ?4.4 and ?5.4, process for the preparation of 2-[2-(1,4-benzodioxanyl)]-2-imidazoline, pharmaceutical compositions thereof or of its salts, and their use as presynaptic .alpha.2-adrenoreceptor antagonists.
369899
Chapleo Christopher B.
Myers Peter L.
Fetherstonhaugh & Co.
Reckitt & Colman Products Limited
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