Imidazolinone and hydantoine derivatives as novel inhibitors...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 401/14 (2006.01) A61K 31/4166 (2006.01) A61P 35/00 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2608929

This invention comprises the novel compounds of Formula (I) wherein R1, R2, R3, X, Y and Z have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.

La présente invention a pour objet les nouveaux composés de Formule (I) où R1, R2, R3, X, Y et Z sont tels que définis dans l'invention, lesdits composés présentant une activité inhibitrice de l'enzyme histone désacétylase. La présente invention a également pour objet l'élaboration desdits composés, les préparations les contenant et leur emploi en tant que médicament.

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