C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/4166 (2006.01) A61P 35/00 (2006.01) C07D 413/14 (2006.01)
Patent
CA 2608929
This invention comprises the novel compounds of Formula (I) wherein R1, R2, R3, X, Y and Z have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
La présente invention a pour objet les nouveaux composés de Formule (I) où R1, R2, R3, X, Y et Z sont tels que définis dans l'invention, lesdits composés présentant une activité inhibitrice de l'enzyme histone désacétylase. La présente invention a également pour objet l'élaboration desdits composés, les préparations les contenant et leur emploi en tant que médicament.
Angibaud Patrick Rene
Marconnet-Decrane Laurence Francoise Bernadette
Meerpoel Lieven
Ten Holte Peter
Van Emelen Kristof
Gowling Lafleur Henderson Llp
Janssen Pharmaceutica N.v.
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