C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/10 (2006.01) A61K 31/4184 (2006.01) A61K 31/4188 (2006.01) A61K 31/4353 (2006.01) A61K 31/444 (2006.01) A61P 25/06 (2006.01) C07D 209/96 (2006.01) C07D 403/06 (2006.01) C07D 471/20 (2006.01) C07D 491/107 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2746671
The present invention is directed to imidazolinone derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
La présente invention concerne des dérivés d'imidazolinone qui sont des antagonistes des récepteurs CGRP et peuvent être employés dans le traitement prophylactique ou thérapeutique de pathologies impliquant CGRP, par exemple la migraine. La présente invention concerne également des compositions pharmaceutiques comprenant lesdits composés, ainsi que l'emploi desdits composés et compositions dans le traitement prophylactique ou thérapeutique de pathologies impliquant les récepteurs CGRP.
Hills Ivory D.
Mcwherter Melody
Selnick Harold G.
Stump Craig A.
Wood Michael R.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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