Imidazolo-5-yl-2-anilinopyrimidines as agents for the...

Details Imidazolo-5-yl-2-anilinopyrimidines as agents for the... Imidazolo-5-yl-2-anilinopyrimidines as agents for the...

C - Chemistry, Metallurgy

07

D

C07D 403/04 (2006.01) C07D 403/14 (2006.01)

Patent

CA 2554076

Compounds of the formula (I), wherein variable groups are as defined within and a pharmaceutically acceptable salts and in vivo hydrolysable esters are described. Also described are processes for their preparation and their use as medicaments, particularly medicaments for producing a cell cycle inhibitory (anti cell proliferation) effect in a warm blooded animal, such as man.

L'invention concerne des composés représentés par la formule (I), dans laquelle les différents groupes sont tels que définis dans le descriptif, et des sels pharmaceutiquement acceptables, et des esters hydrolysables in vivo. L'invention concerne également des procédés de préparation de ces composés, et leur utilisation en tant que médicaments, en particulier pour produire un effet inhibiteur sur le cycle cellulaire (effet anti-prolifération cellulaire) chez les animaux à sang chaud tels que l'homme.

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