Imidazolone derivatives, preparation method thereof and...

Details Imidazolone derivatives, preparation method thereof and... Imidazolone derivatives, preparation method thereof and...

C - Chemistry, Metallurgy

07

D

C07D 405/06 (2006.01) A61K 31/4166 (2006.01) A61K 31/4178 (2006.01) A61P 25/00 (2006.01) C07D 233/96 (2006.01) C07D 317/60 (2006.01) C07D 405/14 (2006.01) C07D 407/10 (2006.01)

Patent

CA 2694377

The invention relates to imidazolone derivatives and the use thereof as drugs, having formula (I), wherein: R1 = H, alkyl at C1 to C5, aryl, or a heterocyclic group with 5 or 6 elements; Ar1 = aryl, optionally substituted, or an aromatic heterocycle; R = R2-S-, R3-HN-, R4COHN or Ar2, with - R2 = an alkyl radical at C1-C5, vinyl or alkyl-vinyl at C1-C5, nitrile or alkyl-nitrile at C1-C5, aryl, benzyl, which are optionally substituted; - R3 = as defined above; and - Ar2 = substituted or non-substituted aryl.

Dérivés d'imidazolones comme médicaments, de formule (I) avec R1 = H, alkyle en C1 à C5; aryle, ou groupe hétérocyclique à 5 ou 6 éléments; Ar1 = aryle, éventuellement substitué; ou hétérocycle aromatique; R = R2-S-, R3-HN-, R4COHN ou Ar2, avec - R2 = un radical alkyle en C1-C5, vinyle ou vinyl-alkyle en C1- C5, nitrile ou nitrile-alkyle en C1-C5, aryle, benzyle, éventuellement substitués; - R3 = les significations données ci-dessus et; Ar2 = aryle substitué ou non.

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