Imidazolone derivatives with activity on central nervous...

Details Imidazolone derivatives with activity on central nervous... Imidazolone derivatives with activity on central nervous...

C - Chemistry, Metallurgy

07

D

167/211, 260/266

C07D 401/06 (2006.01) C07D 233/70 (2006.01) C07D 401/14 (2006.01) C07D 403/06 (2006.01)

Patent

CA 2008610

- 10 - Abstract IMIDAZOLONE DERIVATIVES WITH ACTIVITY ON CENTRAL NERVOUS SYSTEM AND ANTIHYPERTENSIVE ACTIVITY, PREPARATION METHODS THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Invention concerns 4,5-bisubstituted-2-imidazolone derivatives of formula I Image (I) and pharmaceutically acceptable salts thereof, having high affinity in vitro for D2, 5-HT2, 1 receptors and ln vivo activity on central nervous system and antihypertensive activity with negligible secondary effects; methods for the preparation thereof; pharmaceutical formulations containing them.

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