Imidazopyridine paf antagonists

Details Imidazopyridine paf antagonists Imidazopyridine paf antagonists

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/435 (2006.01) A61K 31/535 (2006.01) A61K 31/55 (2006.01) A61K 31/695 (2006.01) C07F 7/08 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2078007

2078007 9117162 PCTABS00008 Compounds of formula (I), wherein A is a C1-C8 alkyl, perfluoroalkyl, cycloalkyl, aryl, substituted aryl, heterocyclic or substituted heterocyclic group; B is defined to include a variety of linking groups including straight and branched-chain alkylene and alkenylene groups as well as groups containing an ether, thio-ether, amine or amide group and various substituted and cyclic variations thereof; and R1, R2 and R3 are each H or CH3; are PAF antagonists of value in the treatment of allergic and inflammatory conditions in humans.

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