Imidazopyridines as cyclin dependent kinase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 35/00 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01)

Patent

CA 2499639

In its many embodiments, the present invention provides a novel class of imidazo[1,2-a]pyridine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.

Dans plusieurs modes de réalisation, l'invention concerne une nouvelle classe de composés imidazo[1,2-a]pyridine utilisés comme inhibiteurs des kinases dépendantes des cyclines (CDK), des procédés de préparation de tels composés, des compositions pharmaceutiques renfermant un ou plusieurs composés susmentionnés, des procédés de préparation de formulations pharmaceutiques renfermant un ou plusieurs composés susmentionnés et des méthodes de traitement, de prévention, d'inhibition ou d'amélioration d'une ou plusieurs maladies associées aux CDK au moyen de tels composés ou compositions pharmaceutiques.

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