Imidazoquinolines containing other heterocyclic groups

Details Imidazoquinolines containing other heterocyclic groups Imidazoquinolines containing other heterocyclic groups

C - Chemistry, Metallurgy

07

D

167/207, 260/251

C07D 471/04 (2006.01) C07D 471/06 (2006.01) C07D 487/04 (2006.01) C07D 487/06 (2006.01)

Patent

CA 1237720

ABSTRACT Compounds of Formula I Image (I) wherein A is a C1-C4 straight or branched alkylene chain which may be saturated or unsaturated, B is a C2-C4 straight or branched alkylene chain which may be saturated or unsaturated, R1 and R2 are the same or different and are hydrogen, aklyl, alkoxy, alkoxyalkyl, hydroxyalkyl, hydroxy, halogen, nitro, carboxy, carboxylic ester, carbamoyl, carbamoyloxy, cyano, acyl, acylamino or trifluoromethyl, Het is a heterocyclic group chosen from imidazolyl, imidazolinyl, benzimidazolyl, thiazolyl, thiazolinyl, quinolyl, piperidyl, pyridyl, benzothiazolyl and pyrimidyl, any of which heterocyclic groups may be substituted, and x is 0 or 1, and pharmaceutically acceptable salts thereof are useful for the treatment of ulcers or hypersecretion in mammals.

469936

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