Imide derivatives

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 233/90 (2006.01) A61K 31/16 (2006.01) A61K 31/275 (2006.01) A61K 31/33 (2006.01) C07C 233/91 (2006.01) C07C 233/92 (2006.01) C07C 235/88 (2006.01) C07C 255/60 (2006.01) C07D 207/26 (2006.01) C07D 207/263 (2006.01) C07D 207/28 (2006.01) C07D 213/40 (2006.01) C07D 213/56 (2006.01) C07D 213/75 (2006.01) C07D 223/10 (2006.01) C07D 233/38 (2006.01) C07D 263/26 (2006.01) C07D 295/155 (2006.01) C07D 307/52 (2006.01) C07D 307/54 (2006.01) C07D 317/66 (2006.01) C07D 333/38 (2006.01)

Patent

CA 2209387

Imide compounds having a propioloyl group or pharmaceutically acceptable salts thereof which exhibit potent activities to inhibit the production of Interleukin 1-.beta. and also the production of Tumor Necrosis Factor .alpha.. These imide compounds are useful as a prophylactic or therapeutic agent for inhibiting the production of Interleukin 1-.beta. and the production of Tumor Necrosis Factor .alpha., typically for such diseases as chronic rheumatism, sepsis, ulcerative colitis, Crohn's disease and many other related diseases in which Interleukin 1-.beta. and/or Tumor Necrosis Factor .alpha. would participate.

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