Imide derivatives, and their production and use

Details Imide derivatives, and their production and use Imide derivatives, and their production and use

C - Chemistry, Metallurgy

07

D

167/223, 260/266

C07D 417/14 (2006.01) A61K 31/495 (2006.01) C07D 275/06 (2006.01) C07D 417/12 (2006.01) C07D 491/18 (2006.01)

Patent

CA 1242724

- 1 - Abstract: The invention provides imide derivatives of the formula Image wherein A is a carbonyl group or a sulfonyl group; B is a group of any one of the formulas: Image (in which E is a methylene group, an ethylene group or an oxygen atom and a full line accompanying a broken line Image indicates a single bond or a double bond), (in which F is a methylene group or an ethylene Image group and a full line accompanying a broken line Image is as defined above) and - 2 - Image (in which R1, R2, R3, R4, R5 and R6 are each a hydrogen atom or a methyl group) when A represents a carbonyl group, or B is a 1,2-phenylene group when A represents a sulfonyl group; D is an ethylene group, an ethenylene group or an ethynylene group, of which one or more may be optionally substituted with hydroxyl; and n is an integer of 0, 1 or 2; or the acid addition salts of the above derivatives. These derivatives and salts are useful for the treatment of psychosis.

505455

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