Imino derivatives of 5-aminobenzodioxole-1, 3 which are...

C - Chemistry – Metallurgy – 07 – D

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260/353.3, 260/2

C07D 405/12 (2006.01) C07D 317/58 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 1152509

ABSTRACT OF THE DISCLOSURE Compounds of the formula Image wherein R1 is an unsaturated heterocyclic radical. Process for preparing these compounds by reacting an aldehyde of the form- ula R1CHO, wherein R1 is selected from the group consisting of: Image and Image and R2 is H or at least one substituent selected from the group consisting of CH3, halogen, and nitro, with an amine having the formula Image in suitable solvent. These compounds are useful in therapy by reason of their analgesic and anti-inflammatory activities and have the advantage of being practically devoid of ulcerogenic activity, in contrast to the classical anti-inflammatories.

356312

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