Immediate release ph-independent solid dosage form of cisapride

Details Immediate release ph-independent solid dosage form of cisapride Immediate release ph-independent solid dosage form of cisapride

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61K 9/48 (2006.01)

Patent

CA 2201264

The present invention concerns oral dosage forms of some particular salts of cisapride, more particularly cisapride-(L)-tartrate, cisapride-(D)-tartrate, cisapride-sulfate, or cisapride citrate, which avoid drugfood interaction and which allow comedication of agents that increase the pH of the stomach. The invention particularly relates to solid oral dosage forms suitable for rapid dissolution. The present invention also concerns tablets which can be prepared via direct compression.

Formes posologiques pour administration orale de certains sels de cisapride, notamment de cisapride-(L)-tartrate, cisapride-(D)-tartrate, cisapride-sulfate ou cisapride-citrate, qui empêchent l'interaction entre médicaments et aliments et permettent la comédication avec des agents augmentant le pH de l'estomac. L'invention porte particulièrement sur des formes posologiques solides pour administration orale, à dissolution rapide. L'invention porte enfin sur des comprimés pouvant être préparés par compression directe.

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