A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/20 (2006.01) A61K 31/397 (2006.01) A61K 31/445 (2006.01) A61K 47/38 (2006.01) A61P 7/02 (2006.01)
Patent
CA 2341397
A new oral IR formulation in solid form for a low molecular weight thrombin inhibitor having pH dependent dissolution, characterized in that the formulation comprises a filler or a combination of fillers having disintegrant properties in an amount higher than 35 % w/w of the formulation.
La présente invention concerne une nouvelle composition administrée oralement, à libération immédiate, pour un inhibiteur de la thrombine à faible poids moléculaire dont la dissolution dépend du pH. Cette composition se caractérise en ce qu'elle comprend un excipient ou une combinaison d'excipients dotés de propriétés délitantes, en doses supérieures à 35 % en poids.
Forsman Sigbrit
Karlsson Christer
Karlsson Magnus
Astrazeneca Ab
Fetherstonhaugh & Co.
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