Immobilisation and application of antigenic carbohydrates to...

G - Physics – 01 – N

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Details

G01N 33/543 (2006.01) G01N 33/531 (2006.01) G01N 33/564 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2667394

The invention relates to the field of chemistry and diagnosis, more in particular to diagnosis of current and/or past and/or symptomless infections or of a history of exposure to a gram-negative -bacterium (such as an enterobacteriaceae or a legionella). Even more in particular, the invention relates to the screening of animals or animal products for the presence of unwanted/undesired microorganisms. The invention further relates to a method for screening samples for the presence of antibodies directed against unwanted/undesired microorganisms and preferably such a method is performed with help of a biosensor. The invention also relates to a method for immobilising polysaccharides to solid surfaces. The invention furthermore provides solid surfaces with immobilised polysaccharides as well as applications of such surfaces.

L'invention a trait au domaine de la chimie et du diagnostic, et concerne plus particulièrement le diagnostic d'infections présentes et/ou passées et/ou sans symptômes, ou d'un historique d'exposition à une bactérie à Gram négatif (telle qu'une entérobactérie ou une légionelle). Plus spécifiquement encore, l'invention concerne la détection de la présence de micro-organismes non voulus/indésirables chez des animaux ou dans des produits animaux. L'invention concerne en outre un procédé pour détecter la présence d'anticorps dirigés contre des micro-organismes non voulus/indésirables dans des échantillons, ce procédé étant de préférence mis en AEuvre à l'aide d'un biocapteur. L'invention concerne aussi un procédé d'immobilisation de polysaccharides sur des surfaces solides. Elle concerne en outre des surfaces solides sur lesquelles sont immobilisés des polysaccharides ainsi que des utilisations de telles surfaces.

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