Immobilization of specific binding assay reagents

Details Immobilization of specific binding assay reagents Immobilization of specific binding assay reagents

G - Physics

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G01N 33/552 (2006.01) C07K 17/14 (2006.01) G01N 33/531 (2006.01) G01N 33/543 (2006.01) G01N 33/545 (2006.01) G01N 33/74 (2006.01) G01N 33/82 (2006.01)

Patent

CA 2133967

2133967 9419693 PCTABS00033 Methods and compositions are provided for specific binding assays in which specific binding reagents are immobilized on a solid phase. Immobilization is facilitated by covalently coupling specific binding assay reagents such as polypeptide receptors or analytes with water soluble polymers. Such water soluble polymers, for example star polymers such as dendrimers, provide production advantages of lot-to-lot uniformity and homogeneity, and can enhance sensitivity due to low non-specific binding to the solid phase.

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