Immobilized biological material

A - Human Necessities – 61 – K

Patent

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167/153, 195/35.

A61K 9/70 (2006.01) A61K 39/385 (2006.01) A61K 39/44 (2006.01) C08G 18/64 (2006.01) C12N 11/08 (2006.01) C12P 1/00 (2006.01) C13K 1/06 (2006.01) C13K 11/00 (2006.01)

Patent

CA 1088008

Abstract of the Disclosure A process for imobilizing a biological material which can be a protein, a coenzyme having at least one primary or secondary amino group per molecule, an admixture of said coenzyme and an enzyme which is mediated by said coenzyme, or an antibiotic having at least one primary or secondary amino group per molecule, wherein the biolog- ical.material is contacted with an excess of an isocyanate- capped liquid polyurethane prepolymer, and the resulting mixture is cured by contacting it with a curing agent to cure the prepolymer and to immobilize the biological mat- erial. The resulting mixture can be cured under foam- forming conditions or under nonfoam-forming conditions. The resulting mixture can be formed into a predetermined shape before or during curing or coated onto a surface before or during curing.

254273

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