Immortalized avian cell lines

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/10 (2006.01) C12N 5/071 (2010.01) A61K 39/00 (2006.01) C12N 7/00 (2006.01) C12N 15/85 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2256038

The invention features non-transformant immortal avian cells, in particular derived from avian tissues, i.e. other than blood or haemotopoietic cells, particularly fibroblasts and epithelial cells, for instance of embryos. The avian cells are immortalized by the SV40 T+t gene in the dependence of the MTI promoter. In particular they integrate the pDAMT vector.

La présente invention a pour objet des cellules aviaires immortelles non transformées, en particulier provenant de tissus aviaires, c'est-à-dire autres que des cellules sanguines ou hématopoïétiques, notamment fibroblastes et cellules épithéliales, par exemple d'embryons. Les cellules aviaires sont immortalisées par le gène SV40 T+t sous la dépendance du promoteur MTI. Elles intègrent notamment le vecteur pDAMT.

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