Immortalized hepatocytes

Details Immortalized hepatocytes Immortalized hepatocytes

C - Chemistry, Metallurgy

12

N

C12N 5/10 (2006.01) A61M 1/38 (2006.01) C12M 3/06 (2006.01) C12Q 1/18 (2006.01) G01N 33/50 (2006.01) A61F 2/02 (2006.01) A61M 1/36 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2247939

The invention features a virally-immortalized mammalian hepatocyte, which is derived from a normal liver cell, has differentiated hepatocyte-specific metabolic activity, has the ability to proliferate, and is nontumorigenic after prolonged culture.

L'invention porte sur un hépatocyte de mammifère viralement immortalisé dérivant d'une cellule hépatique normale mais dont l'activité métabolique, spécifique de l'hépatocyte, est différenciée, qui est capable de proliférer, et reste non tumorogène après une culture prolongée.

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