Immune adjuvant

A - Human Necessities – 61 – K

Patent

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A61K 39/39 (2006.01)

Patent

CA 2636257

A highly safe immune adjuvant exhibiting a potent immunostimulating effect, which comprises two or more different microparticulate immunostimulator carriers and one or more immunostimulators carried on the carriers, respectively, each of the microparticulate immunostimulator carriers comprising the combination of (a) an inorganic substance having such a size that it can be phagocytized by a cell (e.g., microparticulate calcium phosphate) and (b) a precipitate produced by coacervation of a soluble protein and a mucopolysaccharide.

La présente invention concerne un adjuvant immunitaire présentant un haut degré d'innocuité, doté d~un puissant effet immunostimulateur, qui comprend au moins deux véhicules différents d~immunostimulateurs microparticulaires et au moins un immunostimulateur porté sur le véhicule, respectivement, chaque véhicule d~immunostimulateur microparticulaire comprenant l~association composée de (a) une substance inorganique présentant une taille telle qu~elle peut être phagocytée par une cellule (p. ex. du phosphate calcique microparticulaire) et (b) un précipité produit par la coacervation d~une protéine soluble et d~un mucopolysaccharide.

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