C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/078 (2010.01) C12N 5/0783 (2010.01) A61K 35/12 (2006.01) A61K 35/14 (2006.01) A61K 39/00 (2006.01) C12N 5/16 (2006.01)
Patent
CA 2318987
This invention provides a substantially pure population of educated, antigen- specific immune effector cells expanded in culture at the expense of hybrid cells, wherein the hybrid cells are antigen presenting cells (APCs) fused to cells that express one or more antigens and methods of using the population of cells.
L'invention concerne une population sensiblement pure de cellules effectrices immunes, instruites, spécifiques d'antigènes, se développant dans une culture au détriment de cellules hybrides, lesquelles sont des cellules qui présentent un antigène et sont fusionnées à des cellules exprimant un ou plusieurs antigènes. L'invention concerne également des procédés d'utilisation de cette population de cellules.
Gong Jianlin
Kufe Donald
Nicolette Charles A.
Roberts Bruce L.
Dana-Farber Cancer Institute Inc.
Genzyme Corporation
Gowling Lafleur Henderson Llp
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