Immune-enhancing agent for therapeutic use in...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/435 (2006.01) A61K 38/17 (2006.01) A61K 39/39 (2006.01) C07K 14/52 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2131709

A thymus-derived factor from clonal mammalian cell lines of thymic origin, known as TISF, which stimulates, enhances or regulates cell-mediated immune responsiveness, which is preferably substantially homogeneous and purified, and which enhances proliferation and differentiation of lymphocyte and other hematopoietic progenitors and which enhances the response of animals, especially mammalian organisms, to infectious agents and to malignancies. Also disclosed are methods for using TISF in treatment or prevention of disease.

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