Immune modulation device for use in animals

Details Immune modulation device for use in animals Immune modulation device for use in animals

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 39/39 (2006.01)

Patent

CA 2447030

The present invention is directed to an implantable immune modulation device that is useful for modulating an immune response in mammals, comprising a plurality of fibers, within a porous shell. The fiber filling is loaded with single or multiple antigens, and optionally one or more biologically active compounds such as cytokines (e.g. lymphokines, chemokines etc.), attachment factors, genes, peptides, proteins, nucleotides, carbohydrates or cells depending on the application.

L'invention concerne un dispositif de modulation de réponse immunitaire implantable, utile pour moduler une réponse immunitaire chez un mammifère, qui comprend une pluralité de fibres, dans une coque poreuse. La charge de fibres est remplie d'antigènes simples ou multiples, et éventuellement d'un ou plusieurs composés biologiquement actifs du type cytokines (par exemple, lymphokines, chimiokines etc.), facteurs de liaison, gènes, peptides, protéines, nucléotides, hydrates de carbone ou cellules, selon l'application considérée.

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