Immune modulation with class ii alpha-chain fragments

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/74 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) C07K 7/04 (2006.01) C07K 14/47 (2006.01) C07K 16/28 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2169762

Peptides of the alpha subunit of Class II MHC antigens are employed for modulation of T-cell activity. The peptides can be used in therapies, particularly associated with tranplantation by themselves or in conjunction with other agents.

On utilise des peptides de la sous-unité alpha des antigènes du complexe majeur d'histocompatibilité de Classe II pour moduler l'activité des lymphocytes T. On peut utiliser ces peptides dans des thérapies, plus particulièrement associées à la transplantation, seuls ou combinés à d'autres agents.

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