A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4745 (2006.01) A61K 31/437 (2006.01) A61K 31/4748 (2006.01) A61P 11/06 (2006.01) A61P 31/04 (2006.01) A61P 31/10 (2006.01) A61P 33/00 (2006.01)
Patent
CA 2268957
Immune response modifier compounds - imidazoquinoline amines, imidazopyridine amines, 6,7-fused cycloalkylimidazopyridine amines, and 1,2-bridged imidazoquinoline amines - are useful for the treatment of TH2 mediated diseases by administering a therapeutically effective amount of such compounds in order to inhibit TH2 immune response, suppress IL-4/IL-5 cytokine induction and eosinophilia, as well as enhance TH1 immune response.
Des composés modificateurs de la réponse immunitaire tels que les amines imidazoquinoléine, les amines imidazapyridine, les amines 6,7-condensées cycloalkylimidazopyridine et les amines 1,2-pontées imidazaquinoléine sont utiles dans le traitement des maladies induites par les TH2. Ces composés sont administrés en quantité suffisante d'un point de vue thérapeutique de manière à inhiber la réponse immunitaire des TH2, à supprimer l'induction des cytokines IL-4/IL-5 et l'éosinophilie, et à accroître la réponse immunitaire des TH1.
Hammerbeck David M.
Swingle Karl F.
Tomai Mark A.
Minnesota Mining And Manufacturing Company
Robic
LandOfFree
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