Immune response modifier formulations and methods

A - Human Necessities – 61 – K

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Details

A61K 31/4745 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01) A61P 17/12 (2006.01)

Patent

CA 2559607

Pharmaceutical formulations including an immune response modifier (IRM) compound having a 2-aminopyridine moiety fused to a five-membered nitrogen- containing heterocyclic ring; a preservative system including a sorbic acid preservative selected from the group consisting of sorbic acid, esters thereof, salts thereof, and combinations thereof; an antioxidant; and an optional chelating agent.

L'invention concerne des formulations pharmaceutiques contenant un composé modificateur de réponse immunitaire (IRM) possédant une fraction 2-aminopyridine fusionnée à un anneau hétérocyclique contenant de l'azote à cinq éléments; un système de conservation contenant une conservateur à base d'acide sorbique sélectionné dans le groupe constitué d'acide sorbique, d'esters et de sels de cet acide, et de combinaisons de ceux-ci; un antioxydant; et un chélateur facultatif.

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