C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/87 (2006.01) A01K 67/027 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2474901
The present invention provides a method and materials for reproducing an immune response of a mammal against one or more antigens of interest. The method preferably involves cloning a founder mammal and producing an immune response in the clone that is substantially identical to the immune response of the founder animal to the antigen or antigens of interest. Accordingly, a source of valuable antibodies can be maintained despite the death or illness of the antibody producing animal.
L'invention porte sur un procédé et sur des matériaux permettant de reproduire la réponse immunitaire de mammifères vis à vis d'un ou plusieurs antigènes d'intérêt. Ledit procédé consiste de préférence à cloner un mammifère fondateur puis à produire dans le clone une réponse immunitaire identique à celle de l'animal fondateur vis à vis du ou des antigènes d'intérêt. On peut ainsi conserver une source d'antigènes précieux en dépit de la mort ou de la maladie du producteur d'anticorps.
Betthauser Jeffrey M.
Bishop Michael D.
Eilertsen Kenneth
Forsberg Erik J.
Leno Gregory H.
Betthauser Jeffrey M.
Bishop Michael D.
Eilertsen Kenneth
Forsberg Erik J.
Gowling Lafleur Henderson Llp
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