Immuno-stimulant combination for prophylaxis and treatment...

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/39 (2006.01) A61K 39/395 (2006.01) C07H 21/02 (2006.01) C07K 14/52 (2006.01)

Patent

CA 2625506

The invention relates to an immunostimulatory combination for the prophylactics and treatment of hepatitis C. The inventive combination is characterised in that it comprises: a TLR3 agonist, a CD40 agonist and protein NS3 of the hepatitis C virus. The invention also relates to pharmaceutical compositions comprising the aforementioned immunostimulatory combination, to the use of said pharmaceutical compositions and to a kit comprising same. The invention further relates to a method of producing an immune response to the hepatitis C virus and to a vaccine against said virus.

L'invention concerne une combinaison immunostimulatrice pour la prophylaxie et le traitement de l'hépatite C, caractérisée en ce qu'elle comprend : un agoniste du TLR3, un agoniste anti-CD40 et la protéine NS3 du virus de l'hépatite C. L'invention concerne également des compositions pharmaceutiques qui comprennent ladite combinaison immunostimulatrice, l'utilisation de celles-ci et un kit composé desdites compositions pharmaceutiques. L'invention concerne en outre une méthode de production d'une réponse immunitaire au virus de l'hépatite C, et un vaccin contre ledit virus.

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