Immuno stimulating complex and oligonucleotide formulations...

Details Immuno stimulating complex and oligonucleotide formulations... Immuno stimulating complex and oligonucleotide formulations...

A - Human Necessities

61

K

A61K 39/39 (2006.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2572427

Vaccine compositions comprising (a) an oligonucleotide, (b) and immune stimulating complex and (c) an antigen induce a strong interferon-gamma immune response. Both oligonucleotides containing immune stimulatory motifs and oligonucleotides lacking immune stimulatory motifs contribute to an interferon- -gamma response when administered with an immune stimulating complex.

La présente invention se rapporte à des compositions vaccinales, qui contiennent (a) un oligonucléotide, (b) un complexe immunostimulant, et (c) un antigène, et qui induisent une forte réponse immunitaire d'interféron-gamma. Les oligonucléotides contenant des motifs immunostimulants et les oligonucléotides exempts de motifs immunostimulants contribuent à une réponse d'interféron-gamma lorsqu'ils sont administrés avec un complexe immunostimulant.

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